Just over a century ago in Ludwigshafen, Germany, a scientist named Carl Bosch assembled a team of engineers to exploit a new technique in chemistry. A year earlier, another German chemist, Fritz Haber, hit upon a process to pull nitrogen (N) from the air and combine it with hydrogen (H) to produce tiny amounts of ammonia (NH₃). But Haber’s process was delicate, requiring the maintenance of high temperatures and high pressure.

Bosch wanted to figure out how to adapt Haber’s discovery for commercial purposes — as we would say today, to “scale it up.” Anyone looking at the state of manufacturing in Europe around 1910, Bosch observed, could see that the task was daunting: The technology simply didn’t exist.

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